产品货号：
Q50003
中文名称：
兔抗人EGF单抗
英文名称：
Anti-human EGF Antibody
产品规格：
50μL|100μL
发货周期：
1～3天
产品价格：
询价
交叉反应：人
特异性：人EGF
宿主：兔
克隆性：单克隆
纯化方式：蛋白A纯化
制剂：液体
保存条件：-20℃，避免反复冻融
蛋白全称：epidermal growth factor
推荐应用：
背景资料：
EGF is the founding member of the EGF-family of proteins.Members of this protein family have highly similar structural and functional characteristics.EGF contains 9 EGF-like domains and 9 LDL-receptor class B repeats.Human EGF is a 645-Da protein with 53 amino acid residues and three intramolecular disulfide bonds.As a low-molecular-weight polypeptide,EGF was first purified from the mouse submandibular gland,but since then it was found in many human tissues including submandibular gland,parotid gland.It can also be found in human platelets,macrophages,urine,saliva,milk,and plasma.EGF is a growth factor that stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture.It results in cellular proliferation,differentiation,and survival.Salivary EGF,which seems also regulated by dietary inorganic iodine,also plays an important physiological role in the maintenance of oro-esophageal and gastric tissue integrity.EGF acts by binding with high affinity to epidermal growth factor receptor on the cell surface and stimulating the intrinsic protein-tyrosine kinase activity of the receptor.The tyrosine kinase activity,in turn,initiates a signal transduction cascade that results in a variety of biochemical changes within the cell - a rise in intracellular calcium levels,increased glycolysis and protein synthesis,and increases in the expression of certain genes including the gene for EGFR - that ultimately lead to DNA synthesis and cell proliferation.
相关搜索：兔抗人EGF单抗，兔抗人表皮生长因子单克隆抗体，Anti-human EGF Antibody
特异性：人EGF
宿主：兔
克隆性：单克隆
纯化方式：蛋白A纯化
制剂：液体
保存条件：-20℃，避免反复冻融
蛋白全称：epidermal growth factor
推荐应用：
| 应用 | 推荐稀释比例 |
| ELISA | 1:5000-1:10000 |
背景资料：
EGF is the founding member of the EGF-family of proteins.Members of this protein family have highly similar structural and functional characteristics.EGF contains 9 EGF-like domains and 9 LDL-receptor class B repeats.Human EGF is a 645-Da protein with 53 amino acid residues and three intramolecular disulfide bonds.As a low-molecular-weight polypeptide,EGF was first purified from the mouse submandibular gland,but since then it was found in many human tissues including submandibular gland,parotid gland.It can also be found in human platelets,macrophages,urine,saliva,milk,and plasma.EGF is a growth factor that stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture.It results in cellular proliferation,differentiation,and survival.Salivary EGF,which seems also regulated by dietary inorganic iodine,also plays an important physiological role in the maintenance of oro-esophageal and gastric tissue integrity.EGF acts by binding with high affinity to epidermal growth factor receptor on the cell surface and stimulating the intrinsic protein-tyrosine kinase activity of the receptor.The tyrosine kinase activity,in turn,initiates a signal transduction cascade that results in a variety of biochemical changes within the cell - a rise in intracellular calcium levels,increased glycolysis and protein synthesis,and increases in the expression of certain genes including the gene for EGFR - that ultimately lead to DNA synthesis and cell proliferation.
相关搜索：兔抗人EGF单抗，兔抗人表皮生长因子单克隆抗体，Anti-human EGF Antibody